asef 2018

To obtain highly effective new APC-Asef inhibitors, Yang et al. kurs 30 juni 2018 (2018) further optimized MAI-150 via a rational structure-based strategy According to the complex structure of MAI-150/APC (PDB code 5IZ6), the hydrogen atom in the side chain of residue A184 and the oxygen atom in the backbone of residue L185 have a suitable angel (120 9°) and